5 Promising Cannabis Studies (part 2)

D. Lu, HI Ali, et al. from Texas A&M and UConn discussed a new technique of studying and characterizing compounds within cannabis (and beyond) that may affect the CB1 receptor differently than THC. THC is known as an orthosteric agonist or ligand of CB1, meaning THC is the “key” that fits squarely into the CB1 receptor site, or “lock.” However, allosteric ligands are compounds that can bind to the receptor at an alternate site, or locations away from the main “keyhole” to affect the intensity, duration, or character of the biological effect downstream of that receptor.In other words, using these allosteric sites of receptors instead of orthosteric (traditional docking sites) allow for more nuanced responses that emphasize some effects (e.g., anti-inflammatory, anti-pain, etc.), while avoiding other adverse, side effects (e.g., psychoactivity, anxiety, paranoia, etc.).




"If we are not willing to give it to our family, it won't be sold to yours."


© 2019 CBDS Inc.   All Rights Reserved

*Our products should be used only as directed on the label. Consult with your physician or healthcare provider before use especially if you have a serious medical condition, use prescription medications, or are pregnant or nursing. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. By using this site, you agree to follow the Privacy Policy and all Terms & Conditions. Void Where Prohibited by Law. All trademarks and copyrights are property of their respective owners and are not affiliated with nor do they endorse this product.