You may have wondered if you should give CBD to your dog. Does it work, and is it really safe? With the exception of insects humans, and animals have the presence of an endocannabinoid system that act on specific receptor that are found throughout the body, and regulates various physiological roles. Cannabinoids, particularly cannabidiol (CBD), has the potential to treat various medical conditions in a non-toxic way.
THC causes psychoactive effects and harmful for pets, but there is no study reported that CBD is harmful, but rather it is beneficial in many ways. Unlike humans, dogs metabolize cannabinoids in a different way. In dogs, 2-AG and anandamide are the primary messenger cannabinoids. These chemicals activate CB1 and CB2 receptors in the brain, and other regions. Being an agonist to these receptors, CBD weakly binds to these receptors for a longer duration, and evokes long lasting therapeutic response without causing toxic effects. The dog's liver metabolizes the cannabidiol, and eliminate it through the urine, or bile in a sustained , and safe manner.
One study has found that the endocannabinoid system, and cannabinoids could prevent immune mediated, and inflammatory allergic disorders, including skin problems in dogs. A survey study conducted by AHCMA has reported that 61.8% to 95% of pet owners have endorsed the health benefits of CBD for their pets. Some of the medical conditions that were relieved include pain, nervous system problems, inflammation, anxiety, nausea, vomiting, digestive system problems, tumors, seizures, convulsions, skin problems, fireworks, or thunderstorm phobias.
It has been proven that animals share 70% biological homology with humans, so we have some grounds to believe that cannabis could be useful for treating canines.